What is a peptide bond formation mechanism? Provide key steps including condensation reaction and water release.

What is a peptide bond formation mechanism? Provide key steps including condensation reaction and water release.

• A. Amino group attacks carbonyl carbon of the incoming amino acid, forming a covalent amide (peptide) bond and releasing water; occurs during translation on the ribosome.
• B. Carboxyl group attacks amino group forming ester; releasing water; occurs in nucleus.
• C. Hydrogen bond forms between amino groups; no bond formation.
• D. Ribosome creates ionic bonds between side chains.

Answer: (A)